Healing after the Procedure

Healing After The procedure

Wound healing is a natural restorative response to tissue injury. Healing is the interaction of a complete cascade of cellular events that generates resurfacing, reconstitution, and restoration of the tensile strength of injured skin. Healing is a systematic process, traditionally explained in terms of 4 overlapping classic phases: haemostasis, inflammation, proliferation, and maturation.

While platelets play a crucial role in clot formation during haemostasis, inflammatory cells debride (remove) injured tissue during the inflammatory phase. Epithelialisation (forms a barrier), fibroplasia (forming fibrous tissue), and angiogenesis (formation of new blood cells) occur during the proliferative phase. Meanwhile, granulation tissue forms, and the wound begins to contract.

Finally, during the maturation phase, collagen forms tight cross-links to other collagen and with protein molecules, increasing the tensile strength of the wound. For the sake of discussion and understanding, the process of wound healing may be presented as a series of separate events. In fact, the entire process is much more complicated, as cellular events that lead to scar formation overlap.

Haemostasis (phase 1 day)

Haemostasis is the process of the wound being closed by clotting. Haemostasis starts when blood leaks out of the body. The first step of haemostasis is when blood vessels constrict to restrict the blood flow. Next, platelets stick together in order to seal the break in the wall of the blood vessel.

Inflammatory response (phase 1-5 day) 

The second the skin tissue is damaged, Mast cells in the tissue release Histamine to trigger the inflammatory response. At the same time, the capillaries and arterioles begin dilating and release blood plasma into the area as part of the inflammatory response to injury.

The plasma contains nutrients, oxygen, antibodies and white blood cells to help flushes away any foreign matter from the area.

After the initial rush of the inflammatory response, leucocytes and the later arriving macrophages remove the dead tissue and foreign material, and the fibrin net lay down in the tissue is dissolved.

Fibroblastic phase (5-28 days) Also, the Regenerative phase. 

Once the wound is ready to move into the regenerative phase, a sequence of events occurs, and it is all part of the regenerative phase of wound healing, “collagen synthesis”. Collagen, however, cannot be synthesised in the abundance of oxygen and nutrients, and if the blood supply has been damaged, it will need to be replaced.

New Collagen Production 

To produce new collagen, tissue, the fibroblasts that are found in low numbers in the dermis proliferate and migrate to the base of the wound with the help of growth factors and a very important glycoprotein called fibronectin.

Fibronectin acts as a conduit for fibroblasts, and it binds both the wound and the fibroblast together to allow the fibroblast to stay in place (the fibronectin) and take up residence in the wound.

Once in the wound, fibroblasts being to synthesise collagen fibres and produce fibronectin and GAGs like hyaluronic acid.

This dermal remodelling will continue for up to two years from the original injury, with this time-varying individuals and with age. Unfortunately, the scar is rarely as strong as the tissue it replaced.

Stages of Formation Effects 

Stage 1

  • Deterioration of epidermal cells, amorphous collagen, fat cells and muscles
  • Promotion of local blood microcirculation from a few days to a few months
  • Acute leukocyte reactions; the activation of neutrophils and macrophages
  • Activation of reparative processes and tissue immune responses for 6-10 days

Stage 2

  • Activation of metabolism of fibroblasts and increasing of their number
  • Stimulation of synthesis of collagen, elastin, HA for 2-6 months
  • Structural integration of tissues leading to the lifting
  • Lifting effects of sagging tissues

Visible Stages of Formation Effects 

The primary effect is achieved by the presence of strong and elastic threads in the tissues. The result can be noticed after 1-2 weeks. The results are:

  • Improved complexion
  • Skin laxity is improved
  • Skin becomes more elastic and youthful

The results in the skin’s youthfulness will be improved monthly. The results will be different for each individual.

The final result will sustain itself for 12-24 months, dependent on the client’s age and the level of metabolic activity of the cells of the individual’s skin.

Effect of the Final Stage 

Skin rejuvenation:

  • Resolution of wrinkles
  • Tightening of pores
  • Brightening of skin
  • Decrease in the volume of subcutaneous fat
  • Lifting of the skin


The indications for PDO threads are as follows:

  • Facial contouring
    • Cheek enhancement
    • Jawline lift
    • Brow lift
    • Nose augmentation
  • Wrinkle attenuation
    • Crows feet and peri-orbital zone
    • Forehead
    • Cheeks
    • Upper lip
    • Volumisation
  • Skin rejuvenation
  • Skin tightening
  • Pore size-reduction
  • Volume reduction
  • Neck lift
    • Double chin reduction
    • Platysmal relaxation
  • Body contouring
    • Upper arm and chest tightening
    • Abdominal tightening and reduction
    • Cellulite
    • Knee lift
    • Bum lift
    • Breast lift